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…(Scopus)Biochemical Composition and Anticancer Effect of Different Seaweed Species (In-vitro and In-vivo Studies)
T H Ranahewa
Department of Veterinary Pathobiology, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Peradeniya, Sri Lank
A. D. Premarathna
Department of Veterinary Pathobiology, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Peradeniya, Sri Lanka
R.M. K.K. Wijesundara
Department of Veterinary Pathobiology, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Peradeniya, Sri Lanka
V. Wijewardana
Department of Veterinary Pathobiology, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Peradeniya, Sri Lanka; Department of Atomic Energy Agency (IAEA) Vienna, Austria
A. P. Jayasooriya
Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Peradeniya, Sri Lanka; Department of Basic Veterinary Sciences, Faculty of Medical Sciences, University of West Indies, Trinidad and Tobago, West Indies
R.P. V.J. Rajapakse
Department of Veterinary Pathobiology, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Peradeniya, Sri Lanka
DOI: https://doi.org/10.36956/sms.v1i2.94
Received: 1 September 2020; Published: 3 November 2020
Copyright © 2020 T H Ranahewa, A. D. Premarathna, R.M. K.K. Wijesundara, V. Wijewardana, A. P. Jayasooriya, R.P. V.J. Rajapakse. Published by Nan Yang Academy of Sciences Pte. Ltd..
Abstract
Seaweed is an enormous resource comprised with natural bioactive compounds with several therapeutic effects including anticancer activity. In this context, the biochemical composition of seaweed plays a major role. Many biochemical compounds isolated from seaweed, fractions of seaweed and crude extracts has revealed ability of seaweed to fight against several cancer types. In this contrast seaweed extracts inhibit cancer cell growth and proliferation by inducing apoptosis and by inhibiting metastasis activity. In this review, biochemical and anticancer properties of seaweeds are discussed and this will provide the basic information to develop a novel chemotherapeutic drug to challenge the cancers.
Keywords: Seaweed, Biochemical, Bioactive, Anticancer, Apoptosis